Exciting News in Refractive Surgery: Expert Insights on the New Corvis® ST Update Featuring TBI v2

Experts from around the world talk about exciting developments in the integration of corneal biomechanics into clinical practice. In collaboration with 22 study centers worldwide, groundbreaking innovations have been developed to make refractive surgery even safer together with you. Hear how renowned doctors utilize the Corvis® ST in their clinical practice.


  • Prof. Renato Ambrósio Jr
  • Dr. Riccardo Vinciguerra
  • Prof. Rohit Shetty
  • Prof. Dan Reinstein
  • Prof. George Waring IV
  • Dr. Bai Ji
  • Dr. Suphi Taneri

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Artificial Intelligence Integrates Tomography and Biomechanical Assessments for Earlier Ectasia Detection

Prof. Renato Ambrosio, MD, PhD discusses in this white paper the importance and benefits of integrating artificial intelligence into the tomographic and biomechanical assessment of ectasia susceptibility. He explains how AI utilized in the unique combination of Corvis ST and Pentacam supports your decision-making prior to refractive surgery.

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Refractive Camp OCULUS: Tomography meets Biomechanics



Dr. Sven Reisdorf, PhD


  • Prof. Cynthia Roberts, PhD
  • Prof. Renato Ambrosio, MD, PhD
  • Prof. Paolo Vinciguerra, MD
  • Dr. Riccardo Vinciguerra, MD

Four of the world's biggest experts share their knowledge about the importance of corneal tomography and corneal biomechanics for refractive surgery. They discuss interesting clinical cases and explain how they make their clinical decisions based on the most important maps.

Do not miss the opportunity to get insights into the latest developments in this field and watch the webinar here.


World's experts share their thought on new Corvis® ST features

Within this short video the minds behind the Corvis® ST software explain the basic ideas and the scientific background behind the new developments.


Cynthia Roberts, PhD, explains the different clinical applications including screening for normal tension glaucoma. Riccardo Vinciguerra, MD, recaps his work about the Corvis Biomechanical Index (CBI) for the detection of clinical and subclinical keratoconus. The need of artificial intelligence and big data to further optimize the Tomographic Biomechanical Index (TBI) based on Corvis® ST and Pentacam® data is explained by Renato Ambrósio, MD, PhD. The development and validation of a new index to evaluate ectasia risk after laser vision correction was led by Paolo Vinciguerra, MD, who explains the clinical relevance of his work.


Prof. Ahmed Elsheikh, PhD, and Bernardo Lopes, MD, PhD, finally explain how numerical simulations can help in medicine to develop clinical useful solutions such as highly accurate IOP measurements and for the world´s first in-vivo stress-strain measurements.

New Ectasia Screening Software after Laser Vision Correction (LVC)

Pre-operatively, several screening methods exist in order to analyse the risk for developing ectasia after Laser Vision Correction. However, until now limited possibilities exist to evaluate ectasia risk post-operatively.

This software allows an automatic assessment of the biomechanical stability post-operatively.

As a final output the CBI-LVC estimates the risk for an ectasia after laser vision correction. This is an aid for clinical decisions such as corneal crosslinking or laser touch-ups.

Further software updates relevant for refractive surgery include in-vivo stress strain measurements and a biomechanical comparison analysis to monitor progression or stiffening after CXL.

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New Glaucoma Screening Software

The detection of Normal Tension Glaucoma (NTG) is very challenging in clinical practice. Intraocular pressure measurement will not indicate any elevated risk for glaucoma and also the optic nerve head might appear relatively normal. In Europe up to 30 percent of primary open angle glaucoma patients have a normal intraocular pressure, in Asia the incidence of NTG is even higher.

It has been shown recently that biomechanical properties can serve as an independent risk factor for NTG1. This was the basis for the development of the Biomechanical Glaucoma Factor (BGF)².

This parameter gives you a very early risk indicator for NTG and will guide you to the best clinical decisions for your patient.



Riccardo Vinciguerra et al.: Corneal Biomechanics and Biomechanically-corrected Intraocular Pressure in Primary Open Angle Glaucoma, Ocular Hypertension and Controls;  British Journal of Ophthalmology 2019 April 2019.

Pillunat KR, Herber R, Spoerl E, Erb C, Pillunat LE.: A new biomechanical glaucoma factor to discriminate normal eyes from normal pressure glaucoma eyes.  Acta Ophthalmol. 2019 Nov; 97(7)

Sunday Evening Seminar on Corneal Biomechanics in Paris

The seminar will take you on a journey into a new biomechanical world – you will gain detailed insight into corneal biomechanical properties. The internationally well-known experts Prof. Cynthia Roberts, Prof. Renato Ambrósio, Prof. Paolo Vinciguerra, Riccardo Vinciguerra and Bernardo Lopes will share their knowledge and inform you on their latest findings. Furthermore, new software developments of the Corvis® ST will be presented for the first time.

  • Big data and AI: Next generation of TBI
  • World premiere: Stress-strain measurement with the Corvis® ST
  • New Biomechanical Comparison Display and application for CXL
  • Biomechanical assessment post LVC: Stable or ectasia?
  • Case presentations: CBI and TBI in refractive surgery
  • Award for best case report

Since there is only space for 80 attendees, registration is required.

Sunday, 15th September 2019

17:30 h Get-together with finger food
18:00 h to 19:30 h Seminar

Hotel Mercure Paris
Porte de Versailles Expo
36-38 Rue du Moulin
92170 Vanves, France
(Walking distance from hall 7 at Paris Expo Porte de Versailles)

Corneal Biomechanical Properties (German language): The holy grail for refractive surgery?

The holy grail for refractive surgery? Dr. Kiraly from Leipzig discusses in his recent article the importance of corneal biomechanics for screening before refractive surgery. He nicely explains the advantages of corneal biomechanics and the integration of corneal biomechanical properties with tomographic data. Interesting case reports illustrate why the assessment of corneal biomechanical properties is the missing piece to avoid ectasia after refractive surgery.


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New Study illustrates the clinical use of ...

New Study illustrates the clinical use of TBI for enhancing ectasia detection.

New Study illustrates the clinical use of TBI for enhancing ectasia detection. In this groundbreaking paper the development and validation of the tomographic Biomechanical Index (TBI) is described. The data prove the increased sensitivity and specificity for the detection of subclinical keratoconus.

Integration of Scheimpflug-1 based Corneal Tomographic and Biomechanical Assessments for Enhancing Ectasia Detection.

Ambrósio R Jr, Lopes BT, Faria-Correia F, Salomão MQ, Bühren J, Roberts CJ, Elsheikh A, Vinciguerra R, Vinciguerra P
Journal of Refractive Surgery 2017 July 1 33(4): 266-273

Link to the study

Expert Round on Corneal Biomechanics

Expert Round on Corneal Biomechanics

At this round table session, Cynthia Roberts, Renato Ambrósio, Riccardo Vinciguerra and David Kang discuss about the importance of corneal biomechanics in clinical practice and about the latest clinical studies on this topic. If you are interested in this topic you must not miss this video!

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Case series further illustrates the advantage ...

Case series further illustrates the advantage of the biomechanical assessment in cases without topographic or tomographic abnormalities.

Case series further illustrates the advantage of the biomechanical assessment in cases without topographic or tomographic abnormalities. In this case series 12 cases are presented without any tomographic abnormality in one eye but clear ectasia in the other eye. Biomechanical properties were already altered in the tomographic normal eyes.

Biomechanical Characterization of Subclinical Keratoconus Without Topographic or Tomographic Abnormalities

Vinciguerra R, Ambrósio R Jr, Roberts CJ, Azzolini C, Vinciguerra P.
Journal of Refractive Surgery 2017 Jun 1;33(6): 399-407

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Clinical study proves the accuracy of biomechanical corrected IOP after laser vision correction.

Clinical study proves the accuracy of biomechanical corrected IOP after laser vision correction.

Changes in biomechanically corrected intraocular pressure and dynamic corneal response parameters before and after transepithelial photorefractive keratectomy and femtosecond laser-assisted laser in situ keratomileusis

Lee H, Roberts CJ, Kim TI, Ambrósio R Jr., Elsheikh A, Yong Kang DS
Journal of Cataract & Refractive Surgery 2017 Dec;43(12):1495-1503

Link to the study

In this study published by David Kang from Korea the biomechanical changes after tPRK and fs-LASIK were compared. In addition, biomechanical corrected IOP was measured pre-operatively and 6 month post-operatively. The study showed that bIOP was statistically not different compared to the pre-op measurements.

Prof Renato Ambrósio Jr, MD, PhD on the Advantages ...

Prof Renato Ambrósio Jr, MD, PhD on the Advantages of Integrating Tomography and Biomechanics

Prof Renato Ambrósio Jr, MD, PhD on the Advantages of Integrating Tomography and Biomechanics

Three important questions on corneal biomechanics, Prof Ambrósio gives the answers.

  • Can you give a brief update how to detect ectasia based on corneal biomechanics?
  • What is the advantage of integrating tomography and biomechanics?
  • What will be the future of screening for ectasia risk prior to refractive surgery?

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